ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_1 MAIN ABSTRACT TEXT Introduction Somatostatin analogues (SSA’s) are used to treat patients with Neuroendocrine tumours (NET). A potential side effect of their use is biliary stasis and subsequent development of gallstones and therefore routine ultrasound surveillance of the gallbladder is generally recommended for patients treated with SSA’s. It…
Following the annual NESTAC spring meeting, all abstracts presented will be uploaded here. In time we plan to give each abstract a unique DOI as a citable reference for CV and research portfolio purposes.
Details of previously presented abstracts are archived below.
NESS & NESTAC Scientific Day 2022
29th April 2022 – Joint virtual meeting/Institute of Transplantation, The Freeman Hospital
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_2 MAIN ABSTRACT TEXT Introduction Acute pancreatitis (AP) is a potentially life-threatening disease with a high mortality rate. This systematic review aimed to determine efficacy and complications following epidural anaesthesia (EA) in patients with AP. Methods PubMed, EMBASE, SCOPUS and Cochrane library databases were systematically searched between 1992 and…
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_3 MAIN ABSTRACT TEXT Introduction Patients undergoing stoma surgery have higher risk for early readmission. Some patients may benefit from closer post-discharge surveillance to provide early detection of complications and timely intervention. However, there is a paucity of validated tools to identify those at higher risk of readmission. Here,…
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_4 MAIN ABSTRACT TEXT Introduction Livers donated for use in transplantation are underutilised. A lack of clear guidelines regarding the visual assessment of their quality means many ‘borderline’ grafts are needlessly discarded; macroscopic visual assessment by transplanting clinicians is subjective and inconsistent. Deep learning (DL), a form of artificial…
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_5 MAIN ABSTRACT TEXT Introduction There is a paucity of data on the incidence, risk factors, and treatment of splanchnic vein thrombosis (SVT) in acute pancreatitis (AP). Methods All AP admissions between 2018 – 2021 across North East of England were included. Anticoagulation was considered in the presence of…
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_6 MAIN ABSTRACT TEXT Introduction This study evaluated the impact of social deprivation on short- and long-term outcomes in patients with Acute pancreatitis (AP). Methods All AP admissions between 2018-2021 at a high-volume pancreatic centre were analysed. Deprivation (index of multiple deprivation [IMD]) data was sourced from the English…
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_7 MAIN ABSTRACT TEXT Introduction Intraventricular haemorrhage (IVH) is a frequent prematurity complication, potentially leading to hydrocephalus. Treatment for hydrocephalus in IVH varies with temporising methods used to delay definitive shunting, whilst others advocate primary shunting. This retrospective case series compares outcomes between primary and delayed shunting. Methods Premature…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_1 MAIN ABSTRACT TEXT Introduction The most common indication for revision surgery following total hip arthroplasty is aseptic loosening of implants secondary to osteolysis, caused by immune-mediated reactions to implant debris. These debris can cause pseudotumour formation. Toll-like receptor 4 (TLR4) has been shown to mediate immune…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_2 MAIN ABSTRACT TEXT Introduction Surgical rehearsal – patient specific preoperative surgical practice – can be provided by virtual reality (VR) simulation and offers a novel way of increasing the operative volume of surgical trainees. This study investigated the effect of surgical rehearsal on cortical mastoidectomy performance…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_3 MAIN ABSTRACT TEXT Introduction Perioperative hypothermia regularly occurs in hip fracture care despite routine active warming. Few studies have focussed on hypothermia rates in hip fracture surgery, instead, principles from general surgery papers are applied. Methods We performed a retrospective cohort study investigating patient body temperature…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_4 MAIN ABSTRACT TEXT Introduction Femoropopliteal (and femoro-tibial) bypass is a well recognisable and durable surgical option for occluded femoro-popliteal segment. Ipsilateral great saphenous vein, if suitable, has been the most usable graft. It could be reversed or used in situ after valvulotomy. Previous studies have demonstrated…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_5 MAIN ABSTRACT TEXT Introduction A total laryngectomy (TL) involves removal of all laryngeal structures and a portion of the trachea and is typically used to treat locally advanced laryngeal or hypopharyngeal cancer. The literature describes various incisions, but very limited research exists on the impact of…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_6 MAIN ABSTRACT TEXT Introduction The role of vasopressors has long been a subject of debate in microsurgery. Conventional wisdom dictates the avoidance of vasopressor use, due to concerns that by causing peripheral vasoconstriction, inducing vasospasm of the anastomoses and leading to failure in perfusion. It has…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_7 MAIN ABSTRACT TEXT Introduction Surgeon assessment of visual ‘quality of perfusion’ (QOP) influences kidney discard and predicts transplant outcome. However, this assessment is subjective and bias-prone. We aimed to design an “App” utilising a smartphone camera to make this assessment objective and enhance decision making. Methods…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_8 MAIN ABSTRACT TEXT Introduction Fluorescence guided surgery (FGS) for sarcoma resection is an evolving field, with the aim of reducing the positive margin rate and improving patient outcomes. Currently, only non-targeted dyes such as indocyanine green are adopted for clinical use, with known limitations. A sarcoma…
ABSTRACT NUMBER: FEGGETTER MEDAL FOR SENIOR TRAINEES (ST3+)_1 MAIN ABSTRACT TEXT Introduction Otitis media with effusion (OME; ‘glue ear’) is the most common cause of reversible hearing loss in developed countries. In the UK every year 24,000 children undergo surgery (grommets +/- adenoidectomy) for OME. Despite this, the mechanism by which adenoidectomy improves the resolution…
ABSTRACT NUMBER: FEGGETTER MEDAL FOR SENIOR TRAINEES (ST3+)_2 MAIN ABSTRACT TEXT Introduction Perioperative chemotherapy is standard of care in the curative treatment of locally advanced oesophagogastric adenocarcinoma (OGA) in the UK. There is however large number of patients who don’t undergo adjuvant component of both of these perioperative regimens. This study aimed to investigate factors…
ABSTRACT NUMBER: FEGGETTER MEDAL FOR SENIOR TRAINEES (ST3+)_3 MAIN ABSTRACT TEXT Introduction Neoadjuvant chemotherapy (NAC) with the FLOT regimen is increasingly used in the treatment of resectable oesophagogastric cancer (OGC). Histopathological tumour regression (TRG) is associated with a prognostic benefit. There is paucity of data on whether pathological complete response (pCR) rates between FLOT and…
ABSTRACT NUMBER: FEGGETTER MEDAL FOR SENIOR TRAINEES (ST3+)_4 MAIN ABSTRACT TEXT Introduction Esophageal cancer is the seventh most common cancer worldwide with over 570,000 new cases annually. Its pathology is relatively less understood and due to its aggressive nature, the 5-year survival rate is 15–20%. Despite the advancement in diagnostics, intraoperative technology, oncological interventions, and…
NESS & NESTAC Scientific Day 2021
7th May 2021 – joint virtual meeting
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_1 AUTHORS Nasreen Akter MAIN ABSTRACT TEXT Introduction Postoperative pain after major pancreatic resections is frequent. Optimising pain control is a fundamental aspect of Enhanced Recovery After Surgery programmes, which have shown to enhance recovery and reduce morbidity. This systematic review and meta-analysis explored the efficacy of different…
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_2 AUTHOR Prash Cheekoty MAIN ABSTRACT TEXT Introduction Although the incidence and causes of mitral valve repair failure is well documented, the optimal treatment strategy following a failed mitral valve repair remains unclear. This study aims to compare and analyse all available studies which report the clinical outcomes…
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_3 AUTHOR Omar Ali MAIN ABSTRACT TEXT Introduction Surgical site infection contributes to a significant proportion of post-operative morbidity in patients undergoing emergency laparotomy. SSIs cause significant patient burden, increase length of stay and have economic implications. CINPT has been shown to reduce SSI rates in patients undergoing…
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_4 AUTHOR Thejasvin K MAIN ABSTRACT TEXT Introduction There is no consensus regarding the use of nasogastric tube NGT after pancreaticoduodenectomy PD. The present meta-analysis aims to review the current evidence on the impact of routine nasogastric decompression (NGD) following PD on perioperative outcomes. Methods All studies indexed…
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_5 AUTHOR Alexander Lea MAIN ABSTRACT TEXT Introduction Anastomotic leaks (AL) are a complication of colorectal cancer surgery with a mortality rate of 6-39%. Clinical outcomes vary from defunctioning stomas to life-threatening sepsis and death. AL increases the rates of further surgeries and local recurrence of cancer. Multiple…
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_6 AUTHOR Jeremy Cheong MAIN ABSTRACT TEXT Introduction Microcytosis in iron deficiency anaemia triggers an urgent referral for investigation of suspected gastrointestinal cancers. This study evaluated whether the inclusion of hypochromia as a marker for iron deficiency would lead to earlier referrals. Methods Consecutive patients referred from primary…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_1 AUTHOR Ghazaleh Mohammadi-Zaniani MAIN ABSTRACT TEXT Introduction There is emerging evidence that the pancreas may be a target organ of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection. This aim of this study was to investigate the outcome of patients with acute pancreatitis (AP) and co…
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_8 AUTHOR Georgina Liu MAIN ABSTRACT TEXT Introduction Malignant melanoma is the second commonest skin cancer among adults aged 25 to 49 years old. It is crucial for metastatic disease to be detected as early as possible, as the stage of melanoma correlates to the survival rate of…
Pre-fracture mobility is an independent predictor of post-operative outcomes in hip fracture surgery
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_7 AUTHOR Thomas Stubbs MAIN ABSTRACT TEXT Introduction Hip fracture is the most common serious injury in the older population of the UK, and its incidence continues to rise. Previous studies have used preoperative patient characteristics to predict post-operative outcomes, but mobility, a key indicator of pre-operative function,…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_2 AUTHOR Amarkumar Rajgor MAIN ABSTRACT TEXT Introduction Radiotherapy is a well-established treatment for early glottic cancer. However, the majority of published literature combines both stage I (T1N0M0) and stage II (T2N0M0) glottic tumours, thus little is known exclusively regarding the outcomes of stage II (T2N0M0)…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_3 AUTHOR Bertie Marks MAIN ABSTRACT TEXT Introduction Bowel ischaemia is the third most common indication for emergency laparotomy in the UK and is associated with high rates of postoperative morbidity and mortality. This study describes changes in incidence, patient characteristics, management approach and outcomes for…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_4 AUTHOR Ashwin Sivaharan MAIN ABSTRACT TEXT Background This study examined the impact of sarcopenia on clinical outcome in patients who underwent infrainguinal bypass surgery or major lower limb amputation (MLLA). Methods Patients undergoing infra-inguinal bypass and MLLA in 2016-2018 were included in this retrospective analysis.…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_5 AUTHOR Ricardo Fernandes MAIN ABSTRACT TEXT Introduction Almost three quarters of patients diagnosed with bladder cancer have non-muscle invasive disease. The European Association of Urology (EAU) guidelines recommend the use of intravesical instillation of Mitomycin C (MMC) to reduce the rate of recurrence. Methods A…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_6 AUTHOR Samuel Moulding MAIN ABSTRACT TEXT Introduction Liver normothermic machine perfusion (NMP) is being adopted as a method of optimising and assessing livers prior to transplantation. However, there is further potential to utilise the NMP model as a platform for drug delivery. Pregnane X Receptor…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_7 AUTHOR Jakub Chmelo MAIN ABSTRACT TEXT Introduction Treatment for locally advanced oesophagogastric adenocarcinoma (OGA) involves neoadjuvant chemotherapy (NAC) which has a negative impact on patient fitness. Using ‘prehabilitation’ to increase activity levels and fitness may affect physiology, postoperative outcomes and improve patient wellbeing and quality…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_8 AUTHOR Jakub Chmelo MAIN ABSTRACT TEXT Introduction Oesophagectomy is associated with a high rate of morbidity and mortality. Preoperative cardiopulmonary fitness has been correlated with outcomes within major surgery. Variables derived from CPET have been associated with postoperative outcomes. It is unclear whether preoperative cardiorespiratory…
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_9 AUTHOR Beatrice Likupe MAIN ABSTRACT TEXT Introduction NICE guidelines relating to catheter directed thrombolysis for iliofemoral DVT were renewed in March 2020. These state that patients should be considered if they have: symptoms lasting <14 days, good functional status, a life expectancy of 1 year…
ABSTRACT NUMBER: FEGGETTER MEDAL FOR SENIOR TRAINEES (ST3+)_1 AUTHOR Lauren Shelmerdine MAIN ABSTRACT TEXT Introduction Over 3000 Major lower-limb amputation (MLLA) are performed in the UK every year, post-operative pain can limit recovery. Anecdotally, peri-neural catheters (PNC) have lower pain scores than morphine-based patient-controlled analgesia (PCA). This cohort study aimed to identify if PNC…
ABSTRACT NUMBER: FEGGETTER MEDAL FOR SENIOR TRAINEES (ST3+)_2 AUTHOR Ishtiakul Gani Rizvi MAIN ABSTRACT TEXT Introduction Treatment of acute ureteric colic according to current BAUS guidelines can be challenging, particularly during the COVID-19 pandemic. We aim to audit our practice during the initial COVID-19 pandemic. Methods A retrospective analysis of 94 patients admitted with…
ABSTRACT NUMBER: FEGGETTER MEDAL FOR SENIOR TRAINEES (ST3+)_3 AUTHOR Lubna Sayyed Akber Uzzaman MAIN ABSTRACT TEXT Introduction During the Covid-19 pandemic, it was postulated that there might be a delay in cancer patients` presentation, stage migration, changes in management leading to excess mortality in head neck cancer patients (HNC) . However, there is a…
ABSTRACT NUMBER: FEGGETTER MEDAL FOR SENIOR TRAINEES (ST3+)_4 AUTHOR Khalid Munir Bhatti MAIN ABSTRACT TEXT Introduction Barret’s oesophagus (BE) is a precursor of adenocarcinoma of oesophagus. Detection of high-grade dysplasia and adenocarcinoma at an early stage can improve survival but is very challenging. Artificial intelligence (AI) based models have been claimed to improve diagnostic…
ABSTRACT NUMBER: FEGGETTER MEDAL FOR SENIOR TRAINEES (ST3+)_5 AUTHOR Michael Mather MAIN ABSTRACT TEXT Introduction Otitis media (OM) is a leading cause of consultations and surgery in children (Schilder et al., 2016) but translational advances have been hampered by the lack of a physiological model of middle ear epithelium (MEE). Immortalised cell lines (Chun…
ABSTRACT NUMBER: FEGGETTER MEDAL FOR SENIOR TRAINEES (ST3+)_6 AUTHOR Aya Musbahi MAIN ABSTRACT TEXT Introduction No studies have attempted to synthesise all the available surgery related research on robotic surgery in the last twenty years using bibliometrics in a detailed way. The aim of this study is to do a bibliometric analysis of the…
ABSTRACT NUMBER: FEGGETTER MEDAL FOR SENIOR TRAINEES (ST3+)_7 AUTHOR Lubna Sayyed Akber Uzzaman MAIN ABSTRACT TEXT Introduction ACC are low grade cancers with 86.3% arising in parotid and constituting 10% of salivary gland tumors. . Despite having low-grade behaviour, ACCs have a tendency to recur with estimated recurrence rate of around 35%. Surgery is…
ABSTRACT NUMBER: FEGGETTER MEDAL FOR SENIOR TRAINEES (ST3+)_8 AUTHOR Lu Wang MAIN ABSTRACT TEXT Introduction The currently available frailty scores only assess one or selected few of its components. This pilot study aims to assess the feasibility of comprehensively measuring frailty of elective cardiac surgery patients. Methods From December 2018 to September 2020, all…
NESS & NESTAC Scientific Day 2019
3rd May 2019 – Institute of Transplantation, The Freeman Hospital
North East Surgical Training Academy & North East Surgical Society (NESS) May the 3rd 2019 Institute of Transplantation, The Freeman Hospital Abstract/Presentation Marking Prof John Dark, Mr C Wilson, Mr Neil Jennings Provisional Program 12-1pm Buffet Lunch (IOT Level4 Atrium) 1-1.05 Introduction IOT Lecture Theatre J Moir 1.05 …
ABSTRACT NUMBER: NESS_1 AUTHORSKathrin Freystaetter1, Jennifer Mehew2, Sophie Tait1, Omer Senbaklavaci1, John Dark1,3 AFFILIATIONS1 Department of Cardiothoracic Surgery, Freeman Hospital, Newcastle Upon Tyne, United Kingdom2 Statistics and Clinical Studies, NHS Blood and Transplant, Bristol, United Kingdom3 Institute of Transplantation, Freeman Hospital, Newcastle Upon Tyne, United Kingdom CORRESPONDING AUTHOR CONTACT ten.shn@retteatsyerf.nirhtaKLIAME MAIN ABSTRACT TEXTDonor to…
ABSTRACT NUMBER: NESS_2 AUTHOR Miss Rebecca Martin AFFILIATIONS Trauma and Orthopaedics, Royal Victoria Infirmary, Newcastle upon Tyne CORRESPONDING AUTHOR CONTACT EMAIL ku.ca.buq@73nitramr MAIN ABSTRACT TEXT Introduction Neck of femur fractures are a common presentation and certain patients can be managed with a total hip replacement. To receive a total hip replacement the pelvic X-rays…
ABSTRACT NUMBER: NESS_3 AUTHORS Daniel J Lin1,2, James CK Ng2, Lei Huang1, Max Robinson3, James O’Hara2, Janet A Wilson2,4, Andrew L Mellor1 AFFILIATIONS 1. Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK 2. ENT Department, Freeman Hospital, Newcastle upon Tyne, UK 3. Centre for Oral Health Research, Newcastle University, Newcastle upon Tyne, UK…
ABSTRACT NUMBER: NESS_4 AUTHORS Sivesh K Kamarajah, BMedSci MBChB,1, 2 James R Bundred, BMedSci,3 Olivier Saint Marc, MD,4 Long R Jiao, MD FRCS,5 Moh’d Abu Hilal, MD, PhD, FRCS, FACS,6 Derek M Manas, MD FRCS,1 Steven A White, MD, FRCPS FRCS1,2 AFFILIATIONS 1. Department of HPB and Transplant Surgery, The Freeman Hospital, Newcastle upon Tyne,…
ABSTRACT NUMBER: NESS_5 AUTHORS Samuel Tingle, Nina Jordan, Lucy Bates, Katie Cooke, Emily Thompson, Helen M Arthur, Colin Wilson, Neil Sheerin, Simi Ali CORRESPONDING AUTHOR CONTACT EMAIL moc.liamg@elgnitsemajmaS MAIN ABSTRACT TEXT Background: Chronic allograft dysfunction, underpinned by progressive fibrosis, remains a major hurdle in renal transplantation. There is a growing body of research demonstrating…
ABSTRACT NUMBER: NESS_6 AIM To evaluate the outcome of a recent change in practice in the management of acute gallstone disease in a district general hospital METHODS Consecutive patients from August 2017 to July 2018 who presented as an emergency with biliary colic, acute calculous cholecystitis (AUGIS 2015 guidelines) or mild acute gallstone pancreatitis (Revised…
ABSTRACT NUMBER: (NESS _ 07) AUTHORS The Northern Surgical Trainees Research Association AFFILIATIONS The Northern Surgical Trainees Research Association CORRESPONDING AUTHOR CONTACT EMAIL moc.liamg@nabahsoldaf MAIN ABSTRACT TEXT Introduction Traditional treatment of rectal cancer is major surgical resection. The management of early stages has evolved with increasing emphasis on organ preservation, with a number of…
ABSTRACT NUMBER: NESS_8 Authors Nandhra.S, Boylan.L, Prentis. J, Nesbitt. C and the Northern Vascular Centre Introduction Anaemia in elective cardio-vascular surgery has been shown to have a detrimental impact on clinical outcomes and survival. Non-elective caseload is high in vascular surgery and the timely revascularisation in critical limb-ischaemia (CLI) significantly contributes towards this workload.…
ABSTRACT NUMBER: NESS_9 AUTHORS Helen MA Ingoe, William Eardley, Catriona McDaid, Amar Rangan, Catherine Hewitt MAIN ABSTRACT TEXT Surgical fixation of rib fractures (SFRF) is growing in popularity as part of optimising care of patients with rib fractures. There is currently no description of the epidemiology of these injuries at a national level; nor has…
ABSTRACT NUMBER: NESS_12 AUTHORS Emily R Thompson1, Lucy Bates1, Ibrahim K Ibrahim1, Avinash Sewpaul1, Rodrigo Figueriedo1, Ben Stenberg2, Andrew McNeill2, Georgie Wilkins1, Tom Girdlestone1, Henrique de Lamos, Andrew Mellor, Valerie Roobrouck3, Anthony Ting4, Sarah A Hosgood5, Michael L Nicholson5, Andrew J Fisher1, Simi Ali1, Neil Sheerin1, Colin H Wilson AFFILIATIONS 1 NIHR Blood and Transplant…
ABSTRACT NUMBER: NESS_13 AUTHORS Antony K Sorial1, Ines MJ Hofer1, Maria Tselepi1, Eleanor Parker1, Sarah J Rice1, David J Deehan2 and John Loughlin1 AFFILIATIONS 1) Institute of Genetic Medicine, Newcastle University, 2) Freeman Hospital, Newcastle Upon Tyne CORRESPONDING AUTHOR CONTACT EMAIL ku.ca.lcn@lairoS.ynoT MAIN ABSTRACT TEXT Introduction Osteoarthritis (OA) is highly polygenic and OA associated…
ABSTRACT NUMBER: NESTAC_14 AUTHORS Wadah Ali, A Suliman, Stephanie Smith, M Jha AFFILIATIONS James Cook University Hospital CORRESPONDING AUTHOR CONTACT EMAIL ten.shn@ila.hadaW MAIN ABSTRACT TEXT Introduction Abdominal X-rays (AXR) are a routinely requested investigation in the emergency department. There is a common tendency to arrange abdominal x rays in “to complete the work up”…
ABSTRACT NUMBER: NESTAC_15 AUTHORS Farah Mahmoud Ali, Ali Ghareeb, D Garg, Hans Van der Voet, Madan Jha AFFILIATIONS James Cook University Hospital CORRESPONDING AUTHOR CONTACT EMAIL moc.liamg@akzf.haraf MAIN ABSTRACT TEXT Introduction Squamous cell carcinoma (SCC) is the commonest variant of the rather uncommon anal malignancy. Certain disease-related factors have been established in determining…
ABSTRACT NUMBER: NESTAC_01 AUTHORS Umar R1, Gudipati M2 AFFILIATIONS 1Medical Student, Newcastle University, Newcastle Upon Tyne. 2Consultant Obstetrics and Gynaecologist, Sunderland Royal Hospital, Sunderland. CORRESPONDING AUTHOR CONTACT EMAIL ku.shn.tfshc@itapidug.ivadham MAIN ABSTRACT TEXT Background • HMB affects one quarter of women of reproductive age and is one of the most common referrals to secondary care. •…
ABSTRACT NUMBER: NESTAC_02 AUTHORS Miss Bronwyn Woodburn, Miss Oroog Ali, Miss Imogen Cullen, Mr Ryan Ghita, Mr Alastair Hayes, Mr Duncan Light, Miss Kirsty McVey, Mr Fadlo Shaban, Dr Kondo Chilonga, Mr Liam Horgan AFFILIATIONS • Bronwyn Woodburn and Imogen Cullen: Newcastle University, Newcastle, U.K. • Oroog Ali, Alastair Hayes, Duncan Light, Kirsty McVey, Fadlo…
ABSTRACT NUMBER: NESTAC_03 AUTHORS A. Bean, A. Read, A. Sharpe, S. Plusa AFFILIATIONS Colorectal Surgical Unit, Royal Victoria Infirmary, Newcastle upon Tyne Newcastle University, Newcastle upon Tyne CORRESPONDING AUTHOR CONTACT EMAIL ku.ca.eltsacwen@1naeb.a MAIN ABSTRACT TEXT Introduction Stoma formation can be necessary to treat severe constipation and incontinence, but failure of stoma acceptance means reversal,…
ABSTRACT NUMBER: (NESTAC_04) AUTHORS Sherilyn Chew1 David Hamilton2 AFFILIATIONS Faculty of Medical Sciences, Newcastle University1 ENT Department, Freeman Hospital2 CORRESPONDING AUTHOR CONTACT EMAIL ku.ca.eltsacwen@1wehc.S ku.ca.eltsacwen@notlimah.divaD MAIN ABSTRACT TEXT Background The National Institute for Health and Care Excellence (NICE) states that CT thorax is not required in patients with primary T1/T2 laryngeal cancer. Smoking is a…
ABSTRACT NUMBER: NESTAC_05 AUTHORS Timothy Shun Man Chu1, Chad Chang2, Sahan Rannan-Eliya2 AFFILIATIONS Newcastle University1. Department of Plastic and Reconstructive Surgery, Royal Victoria Infirmary2. CORRESPONDING AUTHOR CONTACT EMAIL ku.ca.eltsacwen@1uhC.T MAIN ABSTRACT TEXT Introduction Squamous cell carcinoma (SCC) is the second commonest form of skin cancer. The British Association of Dermatologists (BAD) states that metastatic rate…
ABSTRACT NUMBER: NESTAC_06 AUTHORS Joseph Battle1, Lucy Bates1,2, Professor Neil Sheerin1,2, Professor John Dark1,2 AFFILIATIONS 1 Newcastle University, 2 Freeman Hospital CORRESPONDING AUTHOR CONTACT EMAIL ku.oc.liamtoh@elttabeoj MAIN ABSTRACT TEXT Introduction Acute Kidney Injury (AKI) is common post-cardiac surgery, with up to 30% of cardiac surgery patients going on to develop an AKI. Currently clinicians…
ABSTRACT NUMBER: NESTAC_07 AUTHORS Raiyyan Aftab, Dr Rishab Kapoor, Professor Neil Sheerin AFFILIATIONS Institute of Cellular Medicine, Newcastle University Kidney Research UK CORRESPONDING AUTHOR CONTACT EMAIL ku.ca.eltsacwen@batfa.r MAIN ABSTRACT TEXT Background Acute Kidney Injury (AKI) is associated with increased mortality amongst patients. One of the most common causes of AKI is ischaemia which leads to…
ABSTRACT NUMBER: NESTAC_08 AUTHORS Michaela Paul1, Emily R Thompson1, IK Ibrahim1, Derek M Manas2, Steve A White2, Colin H Wilson1, 2 AFFILIATIONS 1 NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Newcastle University, Newcastle upon Tyne, NE2 4HH 2 Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, NE7 7DN CORRESPONDING AUTHOR…
ABSTRACT NUMBER: NESTAC_09 AUTHORS Sai SJ Wunnava, Stuart M Robinson, Steven A White, Derek M Manas, Peter Littler CORRESPONDING AUTHOR CONTACT EMAIL ku.ca.eltsacwen@avannuw.j.s.s MAIN ABSTRACT TEXT Introduction Hepatic resection remains the gold-standard in management of colorectal liver metastases however thermal ablation is often utilised as an alternative in patients with small volume oligometastatic disease…
ABSTRACT NUMBER: NESTAC_10 AUTHORS Andrew Callaway, Mr Andrew Bowey AFFILIATIONS Newcastle University Medical School CORRESPONDING AUTHOR CONTACT EMAIL moc.liamg@59yawallac.werdnA MAIN ABSTRACT TEXT Background Surgical site infection is a significant and costly complication in spinal surgery. The Royal Victoria Infirmary spinal surgery department uses root cause analysis in each incidence of surgical site infection. Used…
ABSTRACT NUMBER: (NESTAC_11) AUTHORS Shivam Rana AFFILIATIONS Newcastle University (under supervision of Professor Amar Rangan, Orthopaedics Surgeon, James Cook University Hospital) CORRESPONDING AUTHOR CONTACT EMAIL ku.ca.eltsacwen@4anar.s MAIN ABSTRACT TEXT Background Good record keeping is of paramount importance for patient safety and for medico-legal reasons. The diligence with which patient information is recorded may reflect…
ABSTRACT NUMBER: NESTAC_12 AUTHORS Ruth V Owen1, Emily R Thompson1, Samuel J Tingle1, Ibrahim K Ibrahim1, L Bates1, Derek M Manas2, Steve A White2, Colin H Wilson1, 2 AFFILIATIONS 1 NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Newcastle University, Newcastle upon Tyne, NE2 4HH 2 Institute of Transplantation, Freeman Hospital,…
ABSTRACT NUMBER: NESTAC_14 AUTHORS W. Doherty, A. Bowey, P. Sinha, R. Sinclair CORRESPONDING AUTHOR CONTACT EMAIL ku.shn.htun@yewoB.werdnA MAIN ABSTRACT TEXT Background Anaerobic Threshold (AT), quantified through Cardiopulmonary Exercise Testing (CPET), indicates ability to deliver oxygen to metabolizing muscle. AT is used to predict post-operative outcomes across various specialties1; however, its role in Adult Scoliosis…
ABSTRACT NUMBER: NESTAC_15 AUTHORS Gough, M., Holliman, D. AFFILIATIONS Newcastle University, Newcastle upon Tyne Hospitals Trust CORRESPONDING AUTHOR CONTACT EMAIL ku.ca.lcn@3hguog.m MAIN ABSTRACT TEXT Introduction Patients with intracranial metastases from an unknown primary tumour (CUP) are not always given the same treatment and benefits as those provided for patients with metastases of known…
NESS & NESTAC Scientific Day 2018
4th May 2018 – Institute of Transplantation, The Freeman Hospital
DM Bourne, JJ French & Acute Pancreatitis Team (JS Leeds, RM Charnley, K Oppong, M Nayar, J Logue, J Scott, S Saikia, S Young & S McMullen) BackgroundSevere acute pancreatitis, as defined by the revised Atlanta classification,1 is caused by an acute inflammatory process affecting the pancreas gland.2 A recent review of acute pancreatitis1 advocated…
Zakareya Gamie, Anja Krippner-Heidenreich, Craig Gerrand, Kenneth RankinNewcastle University, Northern Institute for Cancer Research, Newcastle upon Tyne, United Kingdom BackgroundDespite intensive, multimodal therapy, patients with bone sarcomas have poor 5-year survival, close to 50%. TNF-related apoptosis-inducing ligand (TRAIL) can induce apoptosis in cancer cells, via the extrinsic pathway, after binding to its death receptors: DR4…
Florence Shekleton, Deena Harji, Ben Griffiths BackgroundMinimally invasive surgical techniques have revolutionised the practice of colorectal surgery. Laparoscopic surgery has led the way followed by the development of robotic-assisted surgery as an alternative approach. Pelvic exenteration is one of the most technically demanding operations reserved for locally advanced and recurrent pelvic malignancy. AimsTo assess the…
Charles Johnson, Ross Mclean, Iain Mcallum, Alexander Phillips BackgroundDuodenal perforation is a common surgical emergency. Open repair with omental patch is routine (1), though laparoscopic repair has been shown to be a safe, reliable alternative (2, 3). Non-operative management is generally restricted to patients too unwell for laparotomy or clinically well at initial assessment (4).…
Nandhra. S, Nesbitt. C, Priona. G, Williams. R, McCaslin. JNorthern Vascular Centre, Freeman Hospital, Newcastle upon Tyne IntroductionComplex endovascular aortic repair is frequently performed using concurrent axillary artery access; this can offer a favourable trajectory for the cannulation of the caudally-orientated visceral vessels. However, associated cerebrovascular complications are reported to be between 2 and 15%.…
RJM Morrison 1,2, D Bunn 3, WK Gray 3, PN Baker 4,5, C White 4, A Rangan 4,5,6, KS Rankin 2, MR Reed 1,2,51 – Department of Orthopaedics, Northumbria Healthcare NHS Foundation Trust, UK 2 – Newcastle University, UK 3 – Research & Development, Northumbria Healthcare NHS Foundation Trust, UK 4 – Department of Orthopaedics,…
Jacob Begbie, Mohammed Fageer IntroductionGallstone related pathology (GD) accounts for a large proportion of general surgery acute admissions, with 3% of acute admissions due to acute cholecystitis (AC). Guidelines from NICE and AUGIS state that AC patients should be offered laparoscopic cholecystectomy (LC) within 7 days of diagnosis (ALC). Despite this, treatment of AC differs…
Samuel Tingle, Avinash Sewpaul, Lucy Bates, Rodrigo Figueiredo, Simi Ali, Neil Sheerin, Colin Wilson Introduction Ischaemia reperfusion injury (IRI) causes significant damage to organs from deceased donors. microRNAs are short non-coding RNAs which each cause repression of many target genes. miR-24-3p and miR-145-5p are two microRNAs with potential detrimental roles in IRI. Our group has…
Bradish T, Kelly C, Paleri V, Robinson M, O’Hara J BackgroundThe 8th edition of the TNM staging system introduced a new staging model for HPV related oropharyngeal squamous cell carcinoma (OPSCC). The dataset original study behind this staging system included patients from 7 centres across North America and Europe[1] ObjectivesThis study aimed to assess how…
Thomas R. Jones (1), Srinivas Annavarapu (2)1 – Newcastle University Medical School, 2 – Royal Victoria Infirmary, Newcastle upon Tyne Paediatric heart transplant (pHTx) is the “gold standard” for children with congenital heart diseases resulting in cardiac failure. However, it is challenging and uncommon and therefore only undertaken in two sites in the UK: The…
N Newton, AW Phillips, H Jaretzke, A Immanuel, N Hayes, SM Griffin BackgroundFollowing a diagnosis of oesophageal cancer UICC TNM staging guides treatment and informs prognosis. There is recognised variance between clinical staging (cTNM) and post-operative pathological staging ((y)pTNM). T3N3 oesophageal cancers have a 5-year survival of less than 25% in most studies; given the…
Jones R, Olatunbode D, Dean J, Hall B, Harji D, Davis P, on behalf of the IMPACT investigators IntroductionIn young adults with indeterminate right iliac fossa (RIF) pain, the need for surgery often relates to the likelihood of appendicitis. Ultrasound (US) is widely used in this setting despite a low diagnostic accuracy for appendicitis. We…
Mr Bertram Marks, Dr FEB May Introduction The incidence of oesophageal adenocarcinoma has increased six-fold over the past 40 years. Despite the increased prevalence, the 5-year mortality is still less than 15% and treatment doesn’t extend much beyond oesophagectomy. Co-activators of Rac1, DOCK2 and ELMO1, were found to be mutated in 17% of oesophageal adenocarcinomas…
JX Lee (1), A Varma (2), P Kane (2)1. Medical School, University of Newcastle2. Department of Neurosurgery, James Cook University Hospital, Middlesbrough BackgroundIn June 2015, National Institute for Health and Care Excellence (NICE) published revised 2WW referral guidelines for general practitioners (GP) for patients with suspected brain and CNS cancer. The comprehensive guidelines include recommendations…
Abdullah K Malik, Steven Masson, Elisa Allen, Murat Akyol, Andrew Bathgate, Mervyn Davies, Ernest Hidalgo, Mark Hudson, James Powell, Agne Zarankaite, Derek M Manas On behalf of the Northern Liver Alliance (NLA) BackgroundThe Northern Liver Alliance (NLA) is a supra-regional allocation system for patients at 3 UK liver transplant centres (Newcastle, Edinburgh and Leeds). Patients…
Espeed Khoshbin, Joseph Battle, Hazel Muse, Kirstie Wallace, George Ditchburn, Gareth Parry, Stephen Clark BackgroundPatient and referring physician choice often means that some lung transplant recipients may reside considerable distances from their transplant centre compared with others. We reviewed a single centre experience to examine the effect of distance from home to the transplant centre…
M.Koziara, AB. Scrimshire, P.Torres IntroductionEXOGEN therapy is established in the management of fracture delayed/non-unions. It has recently been recommended by NICE for use in trauma. Use of EXOGEN in delayed unions in elective foot and ankle surgery has not been previously reported. We aim to review the indications and outcomes of EXOGEN therapy in managing…
Nicole Gull IntroductionThe ALPPS (Associating Liver Partition and Portal vein Ligation for Staged hepatectomy) procedure is a novel surgical approach for the management of primary and secondary liver cancers, first described in the literature in 2012. The aim of this review was to evaluate the effectiveness of ALPPS procedures in our centre and compare our…