ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_7 AUTHOR Jakub Chmelo MAIN ABSTRACT TEXT Introduction Treatment for locally advanced oesophagogastric adenocarcinoma (OGA) involves neoadjuvant chemotherapy (NAC) which has a negative impact on patient fitness. Using ‘prehabilitation’ to increase activity levels and fitness may affect physiology, postoperative outcomes and improve patient wellbeing and quality…
Pregnane X Receptor Activation in Liver Perfusion
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_6 AUTHOR Samuel Moulding MAIN ABSTRACT TEXT Introduction Liver normothermic machine perfusion (NMP) is being adopted as a method of optimising and assessing livers prior to transplantation. However, there is further potential to utilise the NMP model as a platform for drug delivery. Pregnane X Receptor…
The effect of immediate versus early instillation of mitomycin C after transurethral resection of bladder cancer: Is timing everything?
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_5 AUTHOR Ricardo Fernandes MAIN ABSTRACT TEXT Introduction Almost three quarters of patients diagnosed with bladder cancer have non-muscle invasive disease. The European Association of Urology (EAU) guidelines recommend the use of intravesical instillation of Mitomycin C (MMC) to reduce the rate of recurrence. Methods A…
The influence of sarcopenia on lower limb bypass and major lower limb amputation outcomes
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_4 AUTHOR Ashwin Sivaharan MAIN ABSTRACT TEXT Background This study examined the impact of sarcopenia on clinical outcome in patients who underwent infrainguinal bypass surgery or major lower limb amputation (MLLA). Methods Patients undergoing infra-inguinal bypass and MLLA in 2016-2018 were included in this retrospective analysis.…
Ischaemic bowel in the North of England: trends in management approach and patient outcomes
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_3 AUTHOR Bertie Marks MAIN ABSTRACT TEXT Introduction Bowel ischaemia is the third most common indication for emergency laparotomy in the UK and is associated with high rates of postoperative morbidity and mortality. This study describes changes in incidence, patient characteristics, management approach and outcomes for…
Survival Outcomes in Patients with Stage II (T2N0M0) Glottic Cancer Treated with Primary Radiotherapy
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_2 AUTHOR Amarkumar Rajgor MAIN ABSTRACT TEXT Introduction Radiotherapy is a well-established treatment for early glottic cancer. However, the majority of published literature combines both stage I (T1N0M0) and stage II (T2N0M0) glottic tumours, thus little is known exclusively regarding the outcomes of stage II (T2N0M0)…
Pre-fracture mobility is an independent predictor of post-operative outcomes in hip fracture surgery
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_7 AUTHOR Thomas Stubbs MAIN ABSTRACT TEXT Introduction Hip fracture is the most common serious injury in the older population of the UK, and its incidence continues to rise. Previous studies have used preoperative patient characteristics to predict post-operative outcomes, but mobility, a key indicator of pre-operative function,…
Detecting metastatic melanoma with the five-year follow-up regime
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_8 AUTHOR Georgina Liu MAIN ABSTRACT TEXT Introduction Malignant melanoma is the second commonest skin cancer among adults aged 25 to 49 years old. It is crucial for metastatic disease to be detected as early as possible, as the stage of melanoma correlates to the survival rate of…
SARS-CoV-2 infection in acute pancreatitis increases disease severity and 30 day mortality: Results of the COVID PAN collaborative study
ABSTRACT NUMBER: NESS PRIZE FOR JUNIOR TRAINEES (BELOW ST3)_1 AUTHOR Ghazaleh Mohammadi-Zaniani MAIN ABSTRACT TEXT Introduction There is emerging evidence that the pancreas may be a target organ of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection. This aim of this study was to investigate the outcome of patients with acute pancreatitis (AP) and co…
Hypochromia is an early marker of iron deficiency anaemia
ABSTRACT NUMBER: NESTAC MEDAL FOR MEDICAL STUDENTS_6 AUTHOR Jeremy Cheong MAIN ABSTRACT TEXT Introduction Microcytosis in iron deficiency anaemia triggers an urgent referral for investigation of suspected gastrointestinal cancers. This study evaluated whether the inclusion of hypochromia as a marker for iron deficiency would lead to earlier referrals. Methods Consecutive patients referred from primary…