M.Koziara, AB. Scrimshire, P.Torres IntroductionEXOGEN therapy is established in the management of fracture delayed/non-unions. It has recently been recommended by NICE for use in trauma. Use of EXOGEN in delayed unions in elective foot and ankle surgery has not been previously reported. We aim to review the indications and outcomes of EXOGEN therapy in managing…
Transplant
The impact of regional organ sharing and allocation in the UK Northern Liver Alliance (NLA) on waiting time to liver transplantation and waiting list survival
Abdullah K Malik, Steven Masson, Elisa Allen, Murat Akyol, Andrew Bathgate, Mervyn Davies, Ernest Hidalgo, Mark Hudson, James Powell, Agne Zarankaite, Derek M Manas On behalf of the Northern Liver Alliance (NLA) BackgroundThe Northern Liver Alliance (NLA) is a supra-regional allocation system for patients at 3 UK liver transplant centres (Newcastle, Edinburgh and Leeds). Patients…
Long Distance Relationships – Does The Geographic Distance From The Transplant Centre Affect Lung Transplant Outcomes?
Espeed Khoshbin, Joseph Battle, Hazel Muse, Kirstie Wallace, George Ditchburn, Gareth Parry, Stephen Clark BackgroundPatient and referring physician choice often means that some lung transplant recipients may reside considerable distances from their transplant centre compared with others. We reviewed a single centre experience to examine the effect of distance from home to the transplant centre…
Therapeutic Blockade of microRNA in Kidney Transplantation (NESTAC MEDAL WINNER)
Samuel Tingle, Avinash Sewpaul, Lucy Bates, Rodrigo Figueiredo, Simi Ali, Neil Sheerin, Colin Wilson Introduction Ischaemia reperfusion injury (IRI) causes significant damage to organs from deceased donors. microRNAs are short non-coding RNAs which each cause repression of many target genes. miR-24-3p and miR-145-5p are two microRNAs with potential detrimental roles in IRI. Our group has…